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Genome of Potential Bioterror Agent Sequenced; Highlights Similarities Between Animal, Plant Pathogens
Scientists at TIGR, in collaboration with colleagues at three other research institutes, have determined the complete genomic sequence of Brucella suis, a bacterial pathogen and potential bioterrorism agent that could be targeted against humans or livestock.
Towards the $1,000 Genome: "Hot Topic" Added to TIGR Genome Conference
Meeting Kicks Off With Keynote Lecture By Barry Bloom, Dean of Harvard's School of Public Health, Followed by Panel Discussion On New Sequencing Technologies
Study Identifies Genetic Variation In Tuberculosis Strains
A TIGR comparison of the whole genomes of two strains of the bacterium that causes tuberculosis has found a surprising number of differences, indicating that genetic variation may be more extensive among Mycobacterium tuberculosis isolates than previously thought, and may play an important role in the development of the disease and of human immunity to it.
TIGR Offers Genomics Course
TIGR's genomics course for educators, which is designed to give high school biology teachers a thorough understanding of genomics, will be offered on Saturdays this fall, starting on October 19th.
Sequence Provides Insights Into An Emerging Pathogen's Virulence Mechanism, Allowing for Vaccine Development
An analysis of the whole genome sequence of Streptococcus agalactiae serotype V provides valuable insights into the virulence mechanism of the pathogen, which is a leading cause of pneumonia and meningitis in newborns and the source of life-threatening illnesses in a growing number of adults with deficient immune systems.
TIGR, IBEA, and TCAG to Create New High-Throughput Genomic Sequencing Facility
Center will be test bed for latest DNA sequencing and computing technology
Human sequencing to be conducted to better understand genetic variation
Mapping the Mouse Genome
An international research consortium that includes TIGR has published a comprehensive physical map of the mouse genome that provides an important resource for biomedical researchers. The TIGR team, led by Shaying Zhao, sequenced the BAC ends of the mouse genome.
TIGR's informatics group today posted the third major release (3.0) of the genome annotation for the model plant Arabidopsis thaliana
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Antarctic Epiblog: Leaving McMurdo
Ice formation outside McMurdo Station After we took our samples out at the ice edge, we returned to McMurdo Station for several intense days of demobilization. We had to return all of the large drills, power equipment and camping gear, and spent a considerable time preparing our own gear...
Station IV: The Ice Edge
Our last station in our Ross Sea transect was out at the ice edge, about two miles north of our previous station, Station III. We were interested to see how plankton in the open polynya were different from the phytoplankton we isolated from areas locked in sea-ice. Polynyas are ice-free areas of...
Station III: approaching the ice edge
As we were finishing up our work at Station II, we called MacOps, the radio command center for McMurdo Station, and got a 24 hour weather update: a high to the north of Ross Island was blocking a storm in the south, and we were caught in the middle. The prediction: snow, and lots of it. We had...
Station II, Inaccessible Island
The second storm of our trip hit us while we were packing up Station I for a return to McMurdo. The winds began gusting over 50 miles per hour, and the visibility dropped to near zero. We had already packed up camp, but the orders came in over the radio that Condition 1 had been imposed on the sea...
Kudos to Ken!
涩里番 Professor, Kenneth Nealson, has been selected by the American Society of Microbiology to receive an award that recognizes distinguished accomplishments in interdisciplinary research and training in microbiology. The 2010 David C. White Research and Mentoring Award will be awarded to Ken for...
McMurdo Sound
It took another day for the storm to blow itself out, but by Tuesday the wind and driving snow had abated, and we drove our Pisten Bully back out to our temporary shelter near Cape Evans. It took several hours of digging to clear the snow away from our vehicles, but once we started driving away...
Scientist Spotlight: Greg Wanger
Greg Wanger was 3.7 km below the Earth鈥檚 surface, trapped not only underground but also in a country distant from his native lands of Canada and Liechtenstein. He looked around him. It was very hot and smelled like rotten eggs. As many people do during their graduate careers, Greg pondered the...
Digging out from the storm
The next day offered more snow and wind: we still needed handheld radios anytime we ventured between the warming hut and any of the vehicles. The wind was so strong that snow began drifting up through the dive hole in the warming hut, and the windows completely glazed over with snow. At one point...
Out onto the ice
It took an enormous amount of effort, but on Thursday we ventured out onto the sea ice with our train of sleds and snow machines. The tucker is our strongest (and slowest) vehicle, and it is pulling both our yellow research sled and a pair of snowmobiles. The red Pisten-Bully is pulling a second...
Around Mac-town
We are now fully packed and our mobile research sled is ready to go. We are waiting for some final repairs on the Pisten-Bully which will pull our supply sled. The mobile laboratory sled will be pulled by the Sno-Cat Tucker, which also has cab space for six (riding in the mobile lab would probably...
If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to 涩里番.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥�
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