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Scientists Reveal Molecular Secrets of the Malaria Parasite
Groundbreaking Research Project May Help Boost Vaccine Development
Genome Comparison of Four Campylobacter Strains Yields New Genetic Markers and Clues to Virulence
In a study that could benefit medical and food-safety research, scientists have used the tools of comparative genomics to find new clues about why some strains of the bacterium <em>Campylobacter</em> - which each year cause more than 400 million cases of gastrointestinal disease - are more virulent than others. The analysis is helping researchers develop more comprehensive detection methods for analyzing human and environmental isolates of the bacteria.
Microbe's Genome Reveals Insights Into Ocean Ecology
Unexpected findings about the genetic makeup of a marine microbe have given scientists a new perspective on how bacteria make a living in the ocean - a view that may prove useful in wider studies of marine ecology. The analysis by TIGR and collaborators of the DNA sequence of Silicibacter pomeroyi found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought.
Innovative Metagenomics Strategy Used To Study Oral Microbes
In an innovative new project, TIGR scientists and collaborators are using a metagenomics strategy to explore the complex mix of microbes in the human mouth. The research could help improve the diagnosis and treatment of periodontitis and other oral diseases.
Influenza Genome Sequencing Project Is Launched
TIGR will sequence a large number of human isolates of the influenza virus as part of a landmark influenza genome sequencing project announced Monday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The project aims to help scientists better understand how flu viruses evolve as they spread through the population.
TIGR and Virginia Tech Sign Memorandum for New Alliance
A new alliance between TIGR and Virginia Tech University is expected to enhance the Institute's computational and experimental capacity as well as enrich the university's basic research in the life sciences. The Memorandum of Understanding, announced Monday, anticipates joint research projects, shared use of related facilities, adjunct faculty appointments, and opportunities for students to participate in research.
TIGR's Fraser, Salzberg Honored As AAAS Fellows
TIGR President Claire M. Fraser and Senior Bioinformatics Director Steven L. Salzberg have been named as Fellows of the American Association for the Advancement of Science (AAAS) in recognition of their contributions to genomics and bioinformatics.
Computational Genomics Conference To Attract Leading Scientists
Comparative genomics, sequence assembly, gene expression analysis and genome annotation are among the hot topics to be discussed at the 7th annual Conference on Computational Genomics, which will be held October 21-24 in Reston, VA. The meeting is jointly sponsored by TIGR and The Jackson Laboratory.
J. Craig Venter Announces Consolidation of Three Research Organizations Into One New Not-For-Profit Organization 鈥� The J. Craig Venter Institute
The Center for Advancement of Genomics (TCAG), Institute for Biological Energy Alternatives (IBEA), and J. Craig Venter Science Foundation Joint Technology Center (JTC) consolidated to form 涩里番
Scientists Decipher Genome of Biothreat Pathogen
Highly Regulated Virulence Genes and Genomic Instability Found in the Infectious Horse Pathogen Burkholderia mallei
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Tourist Time in Barcelona!
May 20th 2010 After two weeks on the road, I am back on Sorcerer II as we prepare for the Mediterranean sampling season. We are docked in Port Olympic right in the heart of Barcelona. One aspect of this year's blogs is to share some of the experiences and places we get to visit. We are delayed...
The Great Blizzard Sample of Lake Redon!
May15th 2010 We decided to do the 3 lakes in the Banyoles area first because the weather in the Pyrenees was so bad that we wouldn't have been able to get up the mountain to sample Lake Redon. Lake Redon is a pristine Alpine lake that is sampled weekly by Spanish researchers. On Tuesday May 11th...
Lake Vilar, The Final Lake In Banyoles
May 10th 2010 On Monday May 10th we headed back to sample the last lake in the Banyoles area. Lake Vilar is another meromictic lake located about 1 kilometer (1/2 mile) from Lake Siso and has a maximum depth of 10 meters (32 feet). Sulfide is present during the entire year, although restricted...
Sampling of Lake Banyoles, The Home of the Olympic Rowing in 1992
May 9th 2010 Sunday May 9th was a much better morning than the previous one. Emilio had taken us out to one of the best dinners I have ever eaten, plus the German teenagers were no longer patrolling the hallways all night long. So after a great seafood dinner and a good nights rest we drove back...
Lake Sampling Starts with Lake Siso, Global Lake Sampling (GLS)
May 8th 2010 Early on Saturday May 8th Chris and I headed to the University of Girona, which is located about 69 kilometers (42 miles) from Blanes, to setup our sampling gear in a aboratory on campus. We were a bit exhausted from the long drive the day before and lack of sleep due to lots of...
Back on The Road, Mar Menor to Blanes, Spain
May 7th 2010 After a successful day of sampling in Mar Menor and a great local dinner of lobster paella, Chris and I loaded up the van and got back on the road early Friday morning. We had a 757 kilometer (470 miles) drive ahead of us to arrive in Blanes to meet with a team of collaborators from...
The Green Lagoon — Sampling in Albufera de Valencia
During our sampling in Spain last year Chris and I met up with Francisco Rodriguez-Valera. Francisco had some great suggestions for sampling sites and one of them was Albufera de Valencia, a shallow hypertrophic fresh water lagoon, located just 30 minutes drive south of Valencia . When Francisco...
Road Sampling Starts in Mar Menor, Spain
Before sampling was to resume on Sorcerer II, a 2 week multiple-site road sampling trip was planned. Chris Dupont arrived in Valencia a day after me, in the next two days we would load up a giant rental van and hit the road. On Wednesday May 5th we drove the 322 kilometers (200 miles) from Valencia...
Return to Sorcerer II, The Mediterranean Season
Hello everyone! On May 2nd I flew from San Diego to rejoin Sorcerer II in Valencia Spain. Sorcerer II has been in Spain since our last sample in November, during that time her crew has been very busy upgrading systems and getting the rig certified. Sorcerer II is looking great and is ready for...
Looking for a Few Good Genomes (to sequence)!
The 涩里番 is one of three centers funded by the National Institutes of Allergy and Infectious Disease (NIAID) to provide sequencing and genotyping services to the infectious disease community. We are continually looking for researchers who would like to have organisms of research interest to them...
If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to 涩里番.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥�
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