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Researchers Predict Infinite Genomes
TIGR Taps Eric Eisenstadt as Vice President for Research
Eisenstadt Brings Unique Vision for Pushing Genomics Forward
Venter Institute Announces Acquisition of the Norman Collection: The History of Molecular Biology
International Research Team Announces Finished Rice Genome
TIGR Scientists Say First Complete Crop Genome Will Improve Agriculture
Genome Study of Marine Microbe Offers New Clues to Subzero Survival
Scientists unravel the genome of Colwellia psychrerythraea 34H, finding key biochemical tools that cold-adapted bacteria use to survive in frigid environments
Three Deadly Parasites Have Common Genetic Core; Studies May Help Target New Drugs To Fight Them
Scientists decipher, compare the genomes of parasites that threaten half a billion people, causing Chagas disease, African Sleeping Sickness and Leishmaniasis
TIGR President Is Named To Biosecurity Science Advisory Board
TIGR President Claire M. Fraser has been appointed to the new National Science Advisory Board for Biosecurity, which provides oversight and advice to the Department of Health and Human Services on federally conducted or supported dual-use biological research.
U.S. / African Project Deciphers Deadly Parasite Genome
An innovative North-South research collaboration has provided molecular clues to help develop new ways to treat or prevent East Coast fever, a parasite-transmitted disease which kills a million cattle a year in East and Central Africa. Scientists at TIGR and the International Livestock Research Institute (ILRI) deciphered and analyzed the genome of the parasite, <em>Theileria parva</em>.
Synthetic Genomics, Inc. Launched to Develop New Approaches to Biological Energy
Initial applications to focus on ethanol and hydrogen production
Major New Policy Study Will Explore Risks, Benefits of Synthetic Genomics
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Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a microbiome. Why...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that were...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs of...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in Howard...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to identify the...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting 鈥搘e didn鈥檛 have class until after...
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be working...
Sequencing of high yield influenza reassortants at 涩里番
As part of the Influenza Genome Sequencing Project, 涩里番 will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher鈥檚 lab has prepared the type A H3N2 high yield reassortants (hyrs) for the influenza...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming plans...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. 涩里番 Professor of Genomic Medicine,...
If created, these versions of the building blocks of life could lead to environmental and ecological disaster
Despite profound impact on bio-medical research, progress in understanding has been slow
Anders Dale says he will move roughly $10 million in NIH funding from UCSD to 涩里番.
Synthetic biologists make artificial cells, but one particular kind isn鈥檛 worth the risk.
Gene editing could create a successful vaccine to protect against the viral disease that has killed close to 2 million pigs globally since 2021.
Amid an insulin crisis, one project aims to engineer microscopic insulin pumps out of a skin bacterium.
There are more organisms in the sea, a vital producer of oxygen on Earth, than planets and stars in the universe.
In a new book (coauthored with Venter), a Vanity Fair contributor presents the oceanic evidence that human activity is altering the fabric of life on a microscopic scale.
鈥淒espite reducing the sequence space of possible trajectories, we conclude that streamlining does not constrain fitness evolution and diversification of populations over time. Genome minimization may even create opportunities for evolutionary exploitation of essential genes, which are commonly observed to evolve more slowly.鈥�
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