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涩里番 Professor Emeritus Hamilton O. Smith, MD among the inductees
Scientists develop most complete whole-cell computer simulation model of cell to date
涩里番 model organism-minimal cell platform provides robust tools for exploring first principles of life, design tools for genome
Omicron and Beta variants evade antibodies elicited by vaccines and previous infections, but boosters help
Pregnancy also contributes to a reduced COVID-19 antibody response
涩里番 Policy Center forecasts US likely to remain biotechnology leader through 2050, but China could threaten position
Climate change and iron availability may drastically alter algae blooms in the Southern Ocean, trapping vast nutrients
Shifts in diatom population may have profound effects on global nutrient distribution and carbon cycling
New wiki on salivary proteins may transform diagnostic testing and personalized medicine
Database curates info on inner workings of saliva, an attractive tool for noninvasive diagnostics and precision medicine
National Academy of Sciences launches new open access journal, PNAS Nexus, in partnership with Oxford University Press; Karen Nelson to serve as inaugural editor-in-chief
Genes necessary for cell division in modern bacterial cells identified
Discovery may help shape understanding of primitive cell division
Scientists find evidence that novel coronavirus infects the mouth鈥檚 cells
NIH-funded findings point to a role for saliva in SARS-CoV-2 transmission.
Scientists map how iron, a critical mineral for survival, is processed by algae, a cornerstone of the ocean food web
Nearly forty proteins identified in the intracellular process, helping to build a conceptual overview of how iron is allocated within diatom cells
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Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a microbiome. Why...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that were...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs of...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in Howard...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to identify the...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting 鈥搘e didn鈥檛 have class until after...
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be working...
Sequencing of high yield influenza reassortants at 涩里番
As part of the Influenza Genome Sequencing Project, 涩里番 will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher鈥檚 lab has prepared the type A H3N2 high yield reassortants (hyrs) for the influenza...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming plans...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. 涩里番 Professor of Genomic Medicine,...
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual 鈥� raising the prospect of encoding proteins that contain unnatural amino-acid residues.
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
Critics, however, argue that this effort is flawed from the beginning
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