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涩里番 extends CLC bio site license through 2017
Gordon and Betty Moore Foundation identifies 16 leading scientists to pursue high-risk research in marine microbial ecology
涩里番's Andy Allen among new cohort of investigators
Karen Nelson, Ph.D., Named President, Robert Friedman, Ph.D., Appointed as Chief Operating Officer of 涩里番
Both will report directly to J. Craig Venter, Ph.D., Chairman and Chief Executive Officer
Stanford researchers produce first complete computer model of an organism
A mammoth effort has produced a complete computational model of the bacterium Mycoplasma genitalium, opening the door for biological computer-aided design.
涩里番 Researchers, as Part of NIH Human Microbiome Project Consortium, Publish Papers Detailing the Variety and Abundance of Microbes Living on and in the Human Body
Study Represents Largest Group of Healthy Individuals Studied to Date
涩里番 also Details its Metagenomics Reports (METAREP) Open Source Bioinformatics Tool
Solve 1,000 Protein Structures from Infectious Disease Organisms
A 'B-12 Shot' for Marine Algae? Scientists find key protein for algae growth in the ocean
Scientists have revealed a key cog in the biochemical machinery that allows marine algae at the base of the oceanic food chain to thrive. They have discovered a previously unknown protein in algae that grabs an essential but scarce nutrient out of seawater, vitamin B12.
Richard H. Scheuermann, Ph.D. Joins 涩里番 as Director of Informatics
Like people bustling around busy cities, the thousands of molecules inside our cells are constantly interacting with each other: turning each other on or off, working together, splitting up and networking. Understanding the countless ways in which they do so is a major challenge in biology, but it is fundamental to understanding life. Scientists at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) and colleagues in the International Molecular Exchange (IMEx) consortium are rising to the challenge by offering researchers a freely available set of experimental interaction data that can be queried from a single interface. Reporting in Nature Methods, IMEx partners describe the advantages of their service and invite others to join the effort.
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Evaluating Strain-level Variation of Key Acidogenic Species in Dental Plaque Biofilms
The characterization of the dental plaque microbiome, using traditional 16S rDNA profiling strategies, illustrates both the strengths and the limitations of this method. The central limitation of the 16S rDNA methodology is the inability to decipher strain-level variation within a microbiome. Why...
Cataloguing the Gene Expression Patterns of Dental Plaque Biofilms: A Reference Dental Plaque Transcriptome
The RNA-Seq method has been widely adopted as an alternative to the use of DNA microarrays. In most contexts, the RNA-Seq method is implemented when a single reference organism is being studied. Our project endeavored to establish working methods to enable the generation of cDNA libraries that were...
Surrogate Methods for Profiling Species of the Oral and Gut Microbiome
We engaged in an effort focused on alleviating a substantial barrier facing the human microbiome research community. While powerful, the 16S rDNA gene is insufficiently divergent to allow discrimination of many species and essentially no strains present within communities. The increasing costs of...
The Mobile Lab Is Going to Sunny San Diego
Late one evening in January 2006, the mobile lab pulled into the parking lot at 9704 Medical Center Drive. It was such an exciting evening! Within a few days, we had all the lab supplies on it and began visiting students. The first school in the Washington Area was Patapsco Middle School in Howard...
The Hill School: Day 2
The day started early Tuesday with first period. Thirty eager students arrived on the bus to determine the results of the amplification of the DNA they extracted the day before. The PCR ran overnight, copying part of a conserved gene in plants, RuBisCo, that can be used to identify the...
The Hill School: Day 1
The day started early with reagent and lab preparation before we even left for school OR had coffee. We expected to do over 100 DNA Extractions as the first step in the DNA Barcoding. We arrived on campus as the first period was starting 鈥搘e didn鈥檛 have class until after...
The Mobile Laboratory Hits the Road
After a hiatus this summer, the Mobile Laboratory hit the road again today for a trip to Pottstown, Pennsylvania. Driving through the rolling hills of northern Maryland into southeastern Pennsylvania, it passed small towns and beautiful foliage. Tomorrow and Tuesday, we will be working...
Sequencing of high yield influenza reassortants at 涩里番
As part of the Influenza Genome Sequencing Project, 涩里番 will be sequencing a large number of high yield influenza reassortants created in the lab of Dr. Doris Bucher at New York Medical College. Dr. Bucher鈥檚 lab has prepared the type A H3N2 high yield reassortants (hyrs) for the influenza...
What Happened to Sorcerer II?!?!
The last time I wrote a Sorcerer II blog was in November when we set sail from Spain to cross the Atlantic Ocean. For all of you that have been worried that we have been at sea for 8 months, relax we made it!! Over the next few days I will update everyone on what has happened and the upcoming plans...
Podcast on Human Genomics
The 2011 Festival of Ideas themed, The Pursuit of Identity, Landscape, History, and Genetics, is held every other year in Melbourne, Australia to inspire scholars and citizens alike in topics ranging from literature and art to science and foreign policy. 涩里番 Professor of Genomic Medicine,...
Artificial intelligence and machine learning will be the keys to unraveling how the human immune system prevents and controls disease
The biggest synthetic genome so far has been made, with a smaller set of amino-acid-encoding codons than usual 鈥� raising the prospect of encoding proteins that contain unnatural amino-acid residues.
By creating a new genome, scientists could create organisms tailored to produce desirable compounds
Critics, however, argue that this effort is flawed from the beginning
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