涩里番

2023 Erickson Conference Abstracts

BIOLOGY

Abstract 1: 鈥淢echanics of Jaywalking鈥.聽 Insiya Nehal, Geana Nicolas, Esmeralda Vazquez and Vanshika Sangal (advised by Dr. Cara Wall-Scheffler, Dept. of Biology). Abstract: This projects aimed to observe change in speed among individuals who attempted to jaywalk or participated in other pedestrian activities. Other factors were taken into consideration such as load carrying, companions, gender, traffic, time of day, or general surroundings. This was done to see how locomotion is affected by different variables and how it affects daily human decision making.

Abstract 2: 鈥淚nvestigating how Mycoplasma genitalium adapts to 5-Nitroimidazole antibiotics through genomic sequencing鈥.聽 Alessandro Rizzi, Cameron Weller and Abhi Kancherla.聽 Abstract: Mycoplasma genitalium (Mg) is an emerging sexually transmitted pathogen that causes urethritis in men and pelvic inflammatory disease in women. In recent years, antibiotic-resistance in Mg has increased. 5-Nitroimidazoles were recently shown to be effective against Mg and are being explored as alternative treatments. In this study, we examined 5-nitroimidazole resistant mutants using MINion whole genome sequencing. We identified several mutations and specifically discuss those in Mg_342, which encodes FMN reductase.

Abstract 3: 鈥淕enetic Origins of 5-Nitroimidazole Resistance in Mycoplasma genitalium G37S鈥.聽 Helena Huong Nguyen, Leanne Binas and Vaughn Poon.聽 Abstract: Mycoplasma genitalium (Mg) is a sexually transmitted pathogen that causes urethritis in men and pelvic inflammatory disease in women. It is developing resistance to current first-line antibiotics making the discovery of alternative treatments important. 5-nitroimidazoles were recently shown to kill Mg at physiologically relevant concentrations. We investigated the resistance mechanisms of Mg to 5-nitroimidazoles using MinION sequencing revealing a mutation in the gene coding for the NADPH-dependent FMN reductase discussed here.

Abstract 4: 鈥淕enomic Analysis of Aggregated Mycoplasma genitalium Strains Locked with Codon-Modified Variable Regions鈥.聽 Julia Gill, Mariah Kelley, Chris Penner and Tyler Speer.聽 Abstract: Mycoplasma genitalium (G37) is a sexually transmitted pathogen responsible for many urogenital diseases. To promote immune evasion, the pathogen undergoes antigenic and phase variation, occurring through homologous recombination between the MgPa operon and nine MgPars. To investigate the effect of decreased antigenic variation on infection persistence, G37L2 was created to reduce homologous recombination. Surprisingly, serial passage of G37L2 formed non-adherent aggregates, prompting investigation into the genomic rationale for this phenotype.

Abstract 5: 鈥淎ntibodies are a Selective Force for Antigenic Variation in Mycoplasma genitalium鈥.聽 Dev Subramanie, Sukhi Lidder, Xing Z. Huang and Kathryn VanMaanen.聽Abstract: Mycoplasma genitalium causes persistent infection in the human reproductive tract. Its antigenic proteins, MgpB and MgpC, are expressed by the MgPa operon. MgPa undergoes antigenic variation, altering MgpB/C鈥檚 shapes. Bacterial samples from two infected pig-tailed macaques were sequenced to examine the role of antibodies in antigenic variation. Only one macaque produced antibodies against MgpB/C. We found more antigenic variation in bacteria growing in the presence of antibodies, suggesting that antibodies select for antigenic variation.

Abstract 6: 鈥淢onoterpenes in Mainland and Blakely Island tree species鈥.聽 Gum Nau, Hannah McSwain and MacKenzie Garrett (advised by Dr. Ryan Ferrer).聽Abstract: Many plant species exhibit chemical defenses that are induced by herbivore damage, constitutively regardless of damage, or both with different chemicals serving complimentary defensive functions. Monoterpene production in some evergreen tree species appears to be induced by environmental conditions, including herbivore damage. Douglas fir (Pseudotsuga menziesii), western redcedar (Thuja plicata), and lodgepole pine (Pinus contorta) are widely distributed across western Washington and are abundant in the San Juan Islands. Blacktail deer (Odocoileus hemionus columbianus) exhibit intense browsing pressure on these and other plant species, especially on Blakely Island, where deer densities far exceed those of mainland populations. Here, we survey the presence, absence, and concentrations of four representative monoterpenes: 伪-pinene, 尾-pinene, limonene, and 尾-caryophyllene in these three evergreen species on Blakely Island and at an urban, mainland park where deer density is low.

Abstract 7: 鈥淐oral Restoration Efforts in Les Village (Bali, Indonesia)鈥.聽 Krysta Reese (advised by Dr. Tim Nelson, Dept. of Biology).聽 Abstract: This project investigates four aspects of coral reef restoration efforts in Les Village. Survivorship based on species and depth was determined for nursery-grown corals. Micro-fragment transplants of several boulder coral species were measured to evaluate growth in two years. New Acropora (a branching coral) transplants were measured to be re-evaluated in two years. Lastly, the success of previous restoration projects were analyzed by tracking the abundance of butterflyfish at different treatment sites.

Abstract 8: 鈥淭he Analysis of Salmon DNA as an Indicator of Mislabeling Rates in 涩里番 Sushi Restaurants鈥.聽 Hannah Buller and Eloisa Nguyen (advised by Dr. Tracie Delgado, Dept. of Biology).Abstract: Salmon mislabeling is prevalent in the food industry, contributing to false advertisement of salmon species such as substituting a cheaper species in place of an expensive species. Self-classified salmon from sushi restaurants in 涩里番 were identified using molecular methods (PCR, gel electrophoresis, DNA sequencing, etc.). The goals of our research project are to 1) determine salmon mislabeling rates and 2) determine the substitution rate of salmon for another fish species in 涩里番.

Abstract 9: 鈥淪almon Mislabeling Rates at Sushi Restaurants in 涩里番鈥.聽 Griffin Ovenell and Lay Paw (advised by Dr. Tracie Delgado, Dept. of Biology).聽 Abstract: 涩里番 prides itself on its quality of salmon. However, mislabeling of salmon species can occur when salmon is served to the consumer such as advertising wild caught salmon but serving farmed salmon. In this study, salmon samples were collected from sushi restaurants from across 涩里番 to determine mislabeling. The species was determined by sequencing the genome using a polymerase chain reaction (PCR) then comparing the product DNA to a genome database.

Abstract 10: 鈥溕-Difluoromethylornithine (DFMO) as an FDA approved metabolic inhibitor in gammaherpesvirus replication鈥.聽 Jasmine Vo and Lay Paw.聽 Abstract: Viruses play a role in as many as 10-15% of all human cancers. Murine gammaherpesvirus-68 (MHV-68) is a natural pathogen that infects mice and shares homology with several human herpesviruses. The Delgado lab shows an alteration of metabolism in MHV-68 infected cells. Metabolomic data shows an increase in polyamine metabolism in infected cells. 蓱-difluoromethylornithine (DFMO) is a clinically relevant metabolic inhibitor drug that blocks polyamine production. This project investigates DFMO as a potential MHV-68 inhibitor.

Abstract 11: 鈥淲ild or farmed? - Salmon mislabeling in sushi restaurants within the 涩里番-metropolitan area鈥.聽 Jewel Garcia (advised by Dr. Tracie Delgado, Dept. of Biology).聽Abstract: Among many aspects, 涩里番 is also known for its salmon. Though many sushi restaurants tend to market their salmon as a specific species, such as king or coho, these restaurants could mislabel their salmon for various reasons. By acquiring samples from sushi restaurants in the 涩里番 area, conducting PCR, and DNA sequencing, our research compares the DNA of each sample to its public advertisement in one of America鈥檚 most reputable salmon hotspots.

Abstract 12: 鈥淓ffects of Leflunomide on Murine Herpesvirus 68 (MHV-68) Lytic Production鈥.聽 Peter Nalivayko and Helena Huong Nguyen.聽 Abstract: Murine Herpesvirus-68 (MHV-68) is a suitable model for studying viral lytic replication in vitro. The Delgado lab鈥檚 metabolomics screen revealed an increase in nucleotide production in MHV-68 infected cells. Leflunomide (LF) is an FDA-approved drug that inhibits de novo pyrimidine synthesis. We investigated LF effects on MHV-68 lytic production in NIH-3T3 cells and found a significant drop in viral production in the LF-treated cells, opening up the possibility of LF as an antiviral medication.

Abstract 13: 鈥淢urine Herpesvirus 68 (MHV-68) infection increases glucose metabolism to promote viral production鈥.聽 Madeleine Splattstoesser.聽 Abstract: Our lab studies Murine Herpesvirus 68 (MHV68) as a model for understanding how oncogenic human herpesviruses alter host cell metabolism to promote viral replication. Previous metabolomics research done in our lab revealed that the host glycolysis pathway is upregulated during viral infection. The goals of this project are 1) determine if glycolysis is increased in MHV-68 infected cells and 2) determine if glucose starvation or glycolytic inhibitor drugs block virus production.

Abstract 14: 鈥淓fficiency of Leflunomide on Inhibiting MHV-68 Viral Production鈥. Vanshika Sangal.聽Abstract: Murine gamma herpesvirus 68, a naturally occurring pathogen of rodents, is a model system used to study how related human herpesviruses cause cancer. A recent metabolomics study in the Delgado lab showed an increase in nucleotide metabolites during MHV-68 infection of host cells. Leflunomide is a clinically relevant drug that inhibits nucleotide production. The goals of this project are to determine if leflunomide treatment blocks MHV-68 production and may be used as an antiviral treatment.

Abstract 15: 鈥淪patial Comparisons in the Behavior and Movement of 鈥楽ounders鈥 Gray Whales in Possession Sound, Washington鈥.聽 Sara Mach (advised by Dr. Eric Long, Dept. of Biology).聽 Abstract: Every spring, a small group of benthic feeding gray whales, nicknamed the 鈥淪ounders,鈥 come to Possession Sound and the surrounding waters to feed on ghost shrimp that live in the sediment throughout the intertidal zone. This research evaluates and combines fourteen years of sighting data from the Ocean Research College Academy (ORCA) with the intent of identifying spatial patterns in gray whale movement and possible correlations with the tides.

Abstract 16: 鈥淎ntibody Reactivity of Primate Sera to Mycoplasma genitalium Adhesin Proteins鈥.聽 Ethan Wood (advised by Dr. Gwen Wood, University of Washington).聽Abstract: Mycoplasma genitalium is a sexually transmitted pathogen that persists in patients despite the presence of serum antibodies. Antibodies to M. genitalium were collected from infected female pig-tailed macaques and bacterial load was measured. The appearance of M. genitalium-specific antibodies in cervical secretions coincided with decreased bacterial load. The antibodies recognized the MgpB and MgpC adhesin proteins. By using ELISAs we hope to determine which segments of these proteins are targeted by an effective antibody response.

Abstract 17: 鈥淕lucose and fructose differentially regulate microglia-neuronal interactions鈥嬧.聽 Itzel Aparicio (advised by Dr. John Douglass, Dept. of Biology).聽 Abstract: Alzheimer鈥檚 disease involves metabolic changes in the brain such as buildup of carbohydrate fructose. It is unclear whether excess fructose impacts neurons and non-neuronal cells that may influence cerebral function. We used in vitroculture of BV-2 microglia, N43/5 neuronal cell lines and different concentrations of glucose and fructose. Our results indicate that microglia exhibit metabolic flexibility in carbohydrate usage, but that fructose specifically induces a neurotoxic phenotype that may ultimately impair brain health.

Abstract 18: 鈥淩elationship Between Maladaptive Behaviors Induced by Chronic Stress and Glial Inflammation鈥.聽 Jakob Wilson (advised by Dr. John Douglass, Dept. of Biology).聽Abstract: Stress has long been known to influence mood and is linked to increased risk of maladaptive behaviors that include suicidal ideation. The neurological mechanism by which this occurs is not yet understood. In this research, we use a rodent stress model and immunofluorescent microscopy to explore whether astrocytes鈥痑nd microglia鈥痷ndergo conformational changes indicative of inflammation that occur in key brain areas that regulate mood and decision-making behaviors.

Abstract 19: Stress Induces Glial Inflammation in Rat Brains Represented by Immunofluorescent Staining鈥.聽 Mariah Kelley and Milan Brkic (advised by Dr. John Douglass, Dept. of Biology and Dr. Phillip Baker, School of Psychology and Family Counseling).聽 Abstract: Chronic stress is linked to suicidal behaviors in humans, but the neurophysiological mechanisms are not fully understood. Rat models exposed to intermittent and chronic stressors were used to investigate whether stress induces inflammation in specific brain regions. Cells like astrocytes and microglia in the nucleus accumbens were analyzed through immunohistochemical staining in post-mortem brains. Results help us understand neurological links between stress and self-harm, and potentially identify therapeutic targets to treat stress-related mental health disorders.

Abstract 20: 鈥淢achine Learning Analysis for Species Differences in Predator-Exposed Rodents鈥.聽 Hoda AbouEich, Bailey Wells and Michael Mains (advised by Dr. Phillip Baker, School of Psychology and Family Counseling).聽 Abstract: Using machine learning analysis, we analyzed both rats and mice of different strain, sex, age, and housing in order to evaluate behavioral differences in exposure to a 3D printed owl predator that surges towards the center of an arena. As the rodent responded to the stimulus, we were able to evaluate behavioral patterns, such as time spent in hiding, freezing, fleeing, or near the walls of the arena. This will allow us to look at the overall movement trajectories prior to and during predator exposure across species.

Abstract 21: 鈥淓ffects of NMDA Inhibition on Rodent Decision-Making and Reward-Seeking Behavior鈥.聽 Seth Foust, Hoda AbouEich, Bailey Wells, Michael Mains, Brandon Goh and Hannah Doble (advised by Dr. Phillip Baker, School of Psychology and Family Counseling).聽Abstract: In this study, we are investigating how NMDA receptor antagonists affect decision-making in Sprague Dawley rats. Rats were trained to choose between levers that dispense sugar pellets at fixed or progressive increased intervals, and then given varying doses of MK-801 (0.06 ml/g, 0.1 ml/g, 0.2ml/g) or saline as a control. We are analyzing how the rats' behavior relates to optimal choices in the task with each dose of MK-801. These findings could help improve our understanding of how NMDA receptor antagonists affect decision-making and reward-seeking behaviors.

Abstract 22: 鈥淩elationship Between Sex and MK-801's Effects on Rats鈥.聽 Erica Sanchez, Emily McCurry and Seth Foust (advised by Dr. Phillip Baker, School of Psychology and Family Counseling).聽 Abstract: In this study, we are investigating the effects of MK-801 on male and female Sprague Dawley rats. According to D鈥橲ouza et al. (2001), females have a stronger reaction to MK-801 than males. Correspondingly, the current study measures the varied effects of MK-801 on rat models using an optimal decision-making task. The rats are injected with doses of MK-801. Then, they choose between a Fixed-Delay (FD) (ten-second intervals) and a Progressive-Delay (PD) lever (one second progressive increase) to receive rewards. We are currently in the process of obtaining results analyzing the relationship between sex and MK-801鈥檚 effects.

Abstract 23: 鈥淥dor discrimination in response to different forms of intentional focus stimuli鈥.聽 Jewel Garcia (advised by Dr. Ryan Ferrer, Dept. of Biology).聽 Abstract: Humans have an incredible ability to differentiate odor mixtures. Both the peripheral and central nervous systems play a role in human olfaction, receiving odors and interpreting odor combinations and environmental contexts, respectively. We tested whether short-term mindfulness meditation increases odor discriminatory ability compared to stimulated distraction through gameplay. We also predicted that increasing odor mixture overlap would decrease discriminatory ability.

Abstract 24: 鈥淯tilizing DNA Barcoding Analysis in Salmon Species to Identify Potential Mislabeling in Sushi Restaurants in 涩里番鈥.聽 Lauryn Keith (advised by Dr. Tracie Delgado, Dept. of Biology).聽 Abstract: The potential mislabeling of salmon in sushi restaurants, such as substituting less expensive species like farmed for wild-caught, is a prevalent issue. The aim of my research is to investigate this matter in 涩里番 sushi restaurants and compare the results with previous studies conducted in the USA. The utilization of DNA isolation, PCR, and sequencing techniques will enable the identification of salmon species through DNA barcoding.

Abstract 25: 鈥淕enomic analysis of a variety of salmon samples from various sushi shops in 涩里番鈥.聽 Andre鈥 Marineau (advised by Dr. Tracie Delgado, Dept. of Biology).聽Abstract: A group of researchers from 涩里番 collected a variety of either wild caught or farmed Salmon samples in the city of 涩里番. The validity of the claimed salmon species was then determined through isolating the Salmon鈥檚 DNA, amplifying the obtained DNA through PCR and then sending it to Fred Hutch for genomic sequencing. The resulting sequences were then examined to the claimed Salmon species genomic sequence through Finch TV.

CHEMISTRY AND BIOCHEMISTRY

Abstract 26: 鈥淚nvestigating Antigenic Epistasis in MgpB-4a-1 Fragments Using Surface Plasmon Resonance鈥.聽 Vincent Chen, Diana Acevedo-Diaz and Chenyang Wei (advised by Dr. Ben McFarland, Dept. of Chemistry and Biochemistry).聽 Abstract: Surface Plasmon Resonance (SPR) will be used to measure antibody antibody-antigen binding activity of MgpB-4a-1 fragments (G37, BVN, IN, BVNIN) with multiple alanine mutations arranged in a 鈥渄ouble mutant set cycle.鈥 Stable mutated fragments were designed using homology modeling in CHM 4361, expressing recombinantly and purified in CHM 4362 and 3410. If both sets lie in a single epitope, the combined mutations will be like the single sets, although different epitopes will produce additive effects.

Abstract 27: 鈥淣i-NTA and FPLC Purification of Recombinant Microbial Protein Fragments for Antibody Binding Studies鈥.聽 Afrah Agraw, Rosemary Chang and Julia Gill (advised by Dr. Ben McFarland, Dept. of Chemistry and Biochemistry). Abstract: Mycoplasma genitalium causes infections with significant anti-microbial resistance (AMR). Four recombinant protein fragments from a constant region in its adhesin were designed, purified, and characterized: wild type (G37), two tetraalanine mutants (BVN and IN), and one combined octaalanine mutant (BVNIN). Protein fragments purified by Ni-NTA and size exclusion FPLC will be utilized in surface plasmon resonance (SPR) antibody binding analyses to measure antibody binding to microbial protein fragments.

Abstract 28: 鈥淗ydrogen Bonding in Sulfur-Containing Compounds鈥.聽 Tyler Speer (advised by Dr. Daniel Schofield, Dept. of Chemistry and Biochemistry).聽 Abstract: Hydrogen bonding is the attractive interaction between a hydrogen atom bonded to a more electronegative atom (X-H), and a second electronegative atom Y. We explore the possibility of SH-bonds acting as hydrogen bond donors by studying the SH-stretching vibrational frequencies in thioacetic acid. These vibrational frequencies are first calculated using ab initio local mode theory and then measured using infrared absorption spectroscopy.

Abstract 29: 鈥淨uantifying Arsenic in marine organisms using Graphite Furnace Atomic Absorption Spectrophotometry and Multipoint External Standard Calibration Method鈥.聽 Jack Nguyen (advised by Dr. Karisa Pierce, Dept. of Chemistry and Biochemistry).聽Abstract: Graphite furnace atomic absorption spectrophotometry (GFAAS) and multipoint external standard calibration method are used to identify and quantify arsenic in samples of marine tissues. Standard algae (IAEA-392), standard scallops (IAEA-452), standard clams (IAEA-461), and unknown clams are quantified. A Chemical modifier was used to suppress matrix effects. The percentage errors for the standards and the predicted concentration of unknown clam or other samples of interest are reported."

Abstract 30: 鈥淪ynthesis and Characterization of B12 Models of Strong N-Donors with Sulfonamide Links鈥.聽 Kaitlyn Liu and Yu-Jin Youn (advised by Dr. Nerissa Lewis, Dept. of Chemistry and Biochemistry).聽 Abstract: B12 compounds are known to accumulate in cancer cells, thus the utilization of B12 for the targeted delivery of cytotoxic or diagnostic agents to tumor sites is very promising. In this study, pyridyl N-donors bearing sulfonamide links (鈥揝O2NH鈥) were coordinated to simple B12 models, (Cl)Co(DH)2(py) (DH = monoanion of dimethylglyoxime), having targeting potential. Five new sulfonamide ligands, pyppzSO2R, were prepared and coordinated with (Cl)Co(DH)2(py) to synthesize (Cl)Co(DH)2(pyppzSO2R) complexes in good yields.

COMPUTER SCIENCE

Abstract 31: 鈥淯sing Deep Neural Networks to Classify Astronomical Images鈥.聽 Andrew Macpherson (advised by Dr. John Lindberg, Dept. of Physics).聽Abstract: I created a Machine Learning program using a Deep Neural Network (DNN) implemented in Keras and TensorFlow to classify astronomical images based on photometric data. Built from scratch, it utilizes existing labeled images to 鈥渓earn鈥 how astronomical bodies differ in appearance and assign them a category.

Abstract 32: 鈥淢ix: The Technology and Ethics Behind a Social Media Platform鈥.聽 Yarra Abozaed, Tyler Watson, Baron Baruwani, Alison Langer and Brad Bowman (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽Abstract: Mix is an app that transforms the way users think of and interact with social networking platforms. Whether you want to connect with like-minded individuals or explore new communities, our platform provides the tools to do so via group and 'interest-centric' features. We鈥檝e designed user profiles to be a compilation of the user's posts across the site, giving each a personal 'blog' feel. Mix provides multi-media posting, which includes images, text, videos, and others.

Abstract 33: Noah Gallo, Colby Nelson, Isaiah Hogue, Nathaniel Kanooni and Tre Carlton (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽 Abstract: Kairos is a fantasy RTS game where the player battles the Corruption spreading across the continent. If left unchecked, corrupted forces will attack the player and overrun their kingdom. The player must build structures and train soldiers to defeat the corrupted enemies, while their mages reclaim the corrupted lands. As the player drives back the Corruption, they will expand their kingdom and gain new resources. With enough effort, the player will purify the world.

Abstract 34: "GPA". Keagan Byers, Nathan Doan, Sarra Gorbenko, Andrew Macpherson, Jonathan Sharpe and Kyle Telnes (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽 Abstract: With GPA - the Graduation Planning App - we aim to significantly simplify the course planning process, both visually and logically. Our website will help students plan classes by suggesting course sequences, showing major requirements, and even helping them find more classes that suit their interests. We want to make exploring college courses an easy and enjoyable experience, without any unneeded stress.

Abstract 35: 鈥淓on鈥檚 End鈥.聽 Jesse Kaikkonen, Aleksandr Kharchuk, Ammanuel Beyene, Andrey Grebenik and Misha Averkin (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽 Abstract: We aim to create a role playing game with a psychologically challenging story, relatable characters, and interesting plot twists. The player will be challenged to engage in strategic combat, parrley in diplomatic wit, and use their creativity and ingenuity to uncover secrets and solve puzzles. The backdrop of the game will be a captivating mythological setting as well as darker themes and many unknown variables that will change the course of the player鈥檚 journey.

Abstract 36: 鈥淓LISA - ECS Lab Inventory System Application鈥.聽 Najib Gajjule, Tu Vo, Dat Sam, Nhu Vo and John Cabanilla (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽 Abstract: ELISA is a management app designed to help 涩里番's ECS lab manage their inventory more efficiently. With ELISA, students can easily reserve the equipment they need, and the inventory manager can track each piece of equipment with who has what and when. ELISA provides real-time data on the current inventory levels and sends notifications to all users about the equipment and reservation status, making the entire process more effective and time-saving.

Abstract 37: 鈥淓nvision鈥.聽 Logan Munoz, Ismail Aden, Anas Hassan, Drew Mitchell and Lesly Morales (advised by Professor Andy Cameron, Dept. of Engineering and Computer Science).聽 Abstract: Envision allows professors and students to drag and drop images of important events into a web application. That application will repeatedly cycle through those images and display them on monitors throughout the building. Department heads can curate what events or requirements they wish to display to students. No stress or hassle of constantly checking Teams and email, and no more students missing out on information that may play a key role in their educational journey.

ENGINEERING

Abstract 38: 鈥淲WS - Water Working System鈥.聽 Violet Kamienski and Tyler Waggle (advised by Dr. James Walker and Dr. Lin Liu, Dept. of Engineering and Computer Science).聽 Abstract: The Water Working Engineers have the goal to design a water filtration system to be implemented into existing water pans located in the rural areas of Kenya. The Water Working System will ensure cleaner water for drinking and other uses. The device will greatly improve health and sanitary conditions in the country and ensure there is no culture shock of NGO involvement.

Abstract 39: 鈥淧ediatric Incentive Spirometer鈥.聽 Rafael Domingo, Jujhar Singh, Nathan Landas and Bianca Ning (advised by Dr. James Walker and Dr. Lin Liu, Dept. of Engineering and Computer Science).聽 Abstract: Working with Lung Technologies to create a modern and interactive spirometer for children ages 4 to 17.

Abstract 40: 鈥淔lat Plate Solar Collector for a Tiny Home鈥.聽 Clarice Nicholas, Crosby Olson, Alvin Dau, Ed Weise and James Poek (advised by Dr. James Walker and Dr. Lin Liu, Dept. of Engineering and Computer Science).聽Abstract: Our project is a solar water heater designed to provide hot running water for the tenants of Pallet Shelter, which is a company who builds tiny houses for the homeless.

Abstract 41: 鈥淎nti-theft for catalytic converter鈥.聽 Josephus Giducos, Tang Nguyen, Ryan Budd and Minh Le (advised by Dr. Lin Liu and Dr. James Walker, Dept. of Engineering and Computer Science).聽Abstract: To combat the ongoing catalytic converter thefts, our system offers comprehensive protection for the converters: full-converter shield made from aerospace-graded material, active motion sensor to detect suspicious actions, and accurate cutting detection mechanism. Upon detecting thefts, loud alarms up to 140dB will be triggered, and user is also notified via SMS.

Abstract 42: 鈥淐PAM鈥.聽 Khusbu Shah, Mohammed Alanaar and Annie Rogers (advised by Kerry Curran, Dept. of Engineering and Computer Science).聽 Abstract:To prevent the development of DVT by designing an improved聽device to passively increase leg circulation, especially for those with limited mobility and 涩里番 who need surgery.聽 Industry sponsor stated that nearly 50% of 涩里番 going into surgery are already predisposed to developing DVT so improving circulation before and after surgery could drastically reduce the risk of DVT. Modify existing industry sponsor's prototype to increase functionality by:聽 1. Designing a smaller electrical system to聽shrink the housing and make the device smaller, more appealing, and more comfortable.聽 2. Selecting a stronger air pump to inflate the聽air bladders.聽3. Implementing a simple user interface聽to make the device more easily adjustable聽and聽comfortable.

HEALTH AND HUMAN PEFORMANCE

Abstract 43: An International Look into the Sexual Attitudes and Beliefs in Nursing Students鈥.聽 Dhyana Kida (advised by Dr. Vicki Aaberg, School of Health Sciences).聽 Abstract: This research investigates the sexual attitudes and beliefs of nursing students from five universities (including SPU) and four countries using the Sexual Attitudes and Beliefs Survey (SABS) as a way of identifying barriers nurses face in their ability to administer sexual healthcare to their patients.

Abstract 44: 鈥淭he Effects of Subscapularis Acute Trigger Point Release on the Ratio of Peak Torque for Internal and External Rotation鈥.聽 Nathan Allas, Liana Castaneda and Jared Hubbell (advised by Dr. Dale Cannavan and Dr. Katie Butte, School of Health Sciences).聽 Abstract: We used an isokinetic dynamometer and kinematic analysis to determine whether myofascial release of the subscapularis provides increases in peak torque and range of motion. This is important for sports performance and the prevention of sport injury within the shoulder cuff

Abstract 45: 鈥淚nvestigating the Relationship Between Balance and Leg Strength in Older Adults鈥.聽 Maya Holmen and Filip Fullerton (advised by Dr. Katie Butte, School of Health Sciences).聽 Abstract: Our study observes the correlation between balance and leg strength in older adults 55 and older. We also observed the correlation between balance and agility as well as other exploratory aims including Diabetes Mellitus, proprioception, sex, BMI, and living environment.

Abstract 46: 鈥淧hysical Activity, Sleep, and Anxiety in College Students鈥.聽 Alec Taylor and Miguel Molina (advised by Dr. Katie Butte, School of Health Sciences).聽 Abstract: The main purpose of our project is to find the correlation between physical activity, anxiety, and sleep using the General Anxiety Disorder-7, Pittsburg Sleep Quality Index, and the Goldin Leisure-Time Exercise surveys specifically to On-Campus students at SPU.

Abstract 47: The effects of a meditation intervention on self-reported subjective and physiological stress in college students鈥.聽 Rory McClelland, Sebastian Vargas and Kara Lau (advised by Dr. Dale Cannavan and Dr. Katie Butte, School of Health Sciences).聽 Abstract: The project examines the relationship between Respiratory Quotient (RQ) and self- reported stress in college students. With a meditation intervention where pre- and post- RQ levels and self-report stress scores are reviewed to analyze changes between the intervention and control condition.

Abstract 48: 鈥淧revalence and Precursors of Pelvic Tilt in College Students鈥.聽 Isabella Rivera and Gabriel Palavecino (advised by Dr. Katie Butte and Dr. Dale Cannavan, School of Health Sciences).聽 Abstract: For our senior capstone project, student researchers examined the prevalence of pelvic tilt amongst college students by examining the degree between the anterior superior iliac spine and posterior superior iliac spine in the sagittal plane. By identifying the relationship between sedentary and active lifestyles as well as biological factors in pelvic tilt, researchers aimed to expand previous SPU research by surveying a large range of current 涩里番 students.

Abstract 49: 鈥淕uess Who's Coming to Clinic? A Retrospective Study of Clinical Companions in a Pediatric Subspecialty Clinic鈥.聽 Meridiana Mendez (advised by Dr. Kathleen Kieran, 涩里番 Children鈥檚 Research Institute).聽 Abstract: A retrospective study on clinical companions at a subspecialty clinic.

MATHEMATICS

Abstract 51: 鈥淓xploring Mathematics Data regarding First Year Courses鈥.聽 Mackenzi Mehlberg (advised by Dr. Brian Gill, Dept. of Mathematics).聽 Abstract: We will be examining first year course retention rates with data provided from the university.

Abstract 52: 鈥淚s D&D Fair鈥.聽 Zachariah Johansen (advised by Dr. John Hossler, Dept. of Mathematics).聽 Abstract: When playing Dungeons & Dragons or any similar tabletop roleplaying game, most systems use a twenty sided dice as the main method of randomness. But what happens if the dice isn't fair? Well, come on this adventure to solve this riddle.

Abstract 53: 鈥淯nderstanding the Beauty of Mathematics by Composing Claude Debussy's Syrinx into Mathematical Equations鈥.聽 Mackenzi Mehlberg (advised by Dr. John Lindberg, Dept. of Physics).聽Abstract: Is mathematics beautiful? Mathematics is seen as cold and calculating, while music is seen as expressive and beautiful. Through composing Claude Debussey's solo flute piece, Syrinx, in terms of mathematical equations, we are going to expand on our own preconceived notions of beauty and answer the question is math beautiful?

Abstract 54: 鈥淭he Making and Counting of Sudoku's鈥.聽 Amanda Dorgan (advised by Professor Sarah McCord, Dept. of Mathematics).聽Abstract: Have you ever wondered how many different variations of a sudoku there are? Looking at the book, Taking Sudoku Seriously, we will dive into a little bit of the math of how Sudoku's are made and how many different boards are out there!

Abstract 55: 鈥淭urn Off the Glow: Predicting the Light Pollution of an Area and Optimizing the Solutions鈥.聽 Carrie Cox, Elias Coppock and Jobi Lo (advised by Dr. Wai Lau, Dept. of Mathematics). 聽Abstract: Our project utilized multivariable Machine Learning techniques to predict the amount of light pollution an area is likely to suffer from based on several factors our group researched. Then, we created a metric to assess which negative impacts of light pollution the area is most likely to suffer the most from. The metric's results allowed us to recommend which strategy or strategies would be most effective based on the specific needs of each location studied.

Abstract 56: 鈥淚CM Problem D: UN Sustainability Goals鈥.聽 Keagan Byers, Evan King and Lamir Magus (advised by Dr. Wai Lau, Dept. of Mathematics).聽 Abstract: The United Nations has 17 Sustainable Development Goals that are created with the intent to help organize efforts to produce better lives for everyone around the globe. Our task in this ICM problem was to analyze the relationships between these goals and suggest priorities for the UN over the next 10 years. We also generalized our analysis process, such that any organization with goals could follow our process in order to implement priorities effectively.

Abstract 59: 鈥淓xamining Data from the American Statical Association DataFest鈥.聽 Mackenzi Mehlberg and Chelsea Metzger (advised by Dr. Brian Gill, Dept. of Mathematics).聽 Abstract: We participated in DataFest, a competition sponsored by the American Statistical Association. We will present our findings from the competition. We are not permitted to disclose any details of the context of the data analyzed until after May 1st.

Abstract 60: 鈥淎n Analysis of [REDACTED}鈥.聽 Evan King, Cynthia Nguyen and Chloe White (advised by Dr. Brian Gill, Dept. of Mathematics).聽 Abstract: Through Datafest, a competition where teams participate in a weekend-long data analysis session, we came up with a few visualizations and insights from a large, messy, and real dataset of real 涩里番 from a data donor. Our team came up with research questions and collaborated to answer our questions within 48 hours. Due to non-disclosure agreements, we cannot reveal specifics until after May 1st.

PHYSICS

Abstract 57: 鈥淗ow efficient are buildings at SPU? Methods and limitations of building efficiency metrics鈥.聽 David Mosoreti (advised by Dr. Lane Seeley, Dept. of Physics).聽 Abstract: In combating climate change, a major step forward has always been finding ways to make buildings more energy-efficient and overall reducing their carbon footprint. In this study I look at the industry standard at measuring energy efficiency, Energy Use Intensity (EUI). I describe EUI鈥檚 methods and limitations and evaluate how it compares to other standards and derived metrics using buildings on 涩里番鈥檚 campus.

Abstract 58: 鈥淯sing a mass-spring model to understand the complex acoustics of an oscillating wine glass鈥.聽 Gavin Priest (advised by Dr. Lane Seeley, Dept. of Physics).聽 Abstract: Every Physics student learns about a mass spring system, which is a good example of simple harmonic motion. But what about more complex systems which also oscillate harmonically? In this presentation we will explore how students can use their knowledge of a mass spring system to make sense of the complex acoustics of a wine glass. We will discuss the role of nodes, antinodes, modes of oscillation and methods for activating those modes.